diff --git a/build-tools/automation/yaml-templates/stage-package-tests.yaml b/build-tools/automation/yaml-templates/stage-package-tests.yaml
index 869ac45cee1..a824c974f39 100644
--- a/build-tools/automation/yaml-templates/stage-package-tests.yaml
+++ b/build-tools/automation/yaml-templates/stage-package-tests.yaml
@@ -199,10 +199,20 @@ stages:
         testName: Mono.Android.NET_Tests-CoreCLR
         project: tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj
         testResultsFiles: TestResult-Mono.Android.NET_Tests-$(XA.Build.Configuration)CoreCLR.xml
-        extraBuildArgs: -p:TestsFlavor=CoreCLR -p:UseMonoRuntime=false
+        extraBuildArgs: -p:TestsFlavor=CoreCLR -p:_AndroidTypeMapImplementation=llvm-ir
         artifactSource: bin/Test$(XA.Build.Configuration)/$(DotNetTargetFramework)-android/Mono.Android.NET_Tests-Signed.aab
         artifactFolder: $(DotNetTargetFramework)-CoreCLR
 
+    - template: /build-tools/automation/yaml-templates/apk-instrumentation.yaml
+      parameters:
+        configuration: $(XA.Build.Configuration)
+        testName: Mono.Android.NET_Tests-CoreCLRTrimmable
+        project: tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj
+        testResultsFiles: TestResult-Mono.Android.NET_Tests-$(XA.Build.Configuration)CoreCLRTrimmable.xml
+        extraBuildArgs: -p:_AndroidTypeMapImplementation=trimmable -p:UseMonoRuntime=false
+        artifactSource: bin/Test$(XA.Build.Configuration)/$(DotNetTargetFramework)-android/Mono.Android.NET_Tests-Signed.aab
+        artifactFolder: $(DotNetTargetFramework)-CoreCLRTrimmable
+
     - template: /build-tools/automation/yaml-templates/apk-instrumentation.yaml
       parameters:
         configuration: $(XA.Build.Configuration)
diff --git a/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JavaObjectExtensionsTests.cs b/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JavaObjectExtensionsTests.cs
index 1b13316cc3d..1ef98e558e7 100644
--- a/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JavaObjectExtensionsTests.cs
+++ b/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JavaObjectExtensionsTests.cs
@@ -15,7 +15,7 @@ namespace Java.InteropTests {
 	[TestFixture]
 	public class JavaObjectExtensionsTests {
 
-		[Test]
+		[Test, Category ("TrimmableIgnore")]
 		public void JavaCast_BaseToGenericWrapper ()
 		{
 			using (var list = new JavaList (new[]{ 1, 2, 3 }))
diff --git a/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JnienvTest.cs b/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JnienvTest.cs
index a563f56fd3a..be5347a780a 100644
--- a/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JnienvTest.cs
+++ b/tests/Mono.Android-Tests/Mono.Android-Tests/Java.Interop/JnienvTest.cs
@@ -121,7 +121,7 @@ public void InvokingNullInstanceDoesNotCrashDalvik ()
 			}
 		}
 
-		[Test]
+		[Test, Category ("TrimmableIgnore")]
 		public void NewOpenGenericTypeThrows ()
 		{
 			try {
@@ -301,7 +301,7 @@ public void ActivatedDirectObjectSubclassesShouldBeRegistered ()
 			}
 		}
 
-		[Test]
+		[Test, Category ("TrimmableIgnore")]
 		public void ActivatedDirectThrowableSubclassesShouldBeRegistered ()
 		{
 			if (Build.VERSION.SdkInt <= BuildVersionCodes.GingerbreadMr1)
diff --git a/tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj b/tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj
index ae33bef1571..31011e1bd97 100644
--- a/tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj
+++ b/tests/Mono.Android-Tests/Mono.Android-Tests/Mono.Android.NET-Tests.csproj
@@ -37,6 +37,12 @@
     <ExcludeCategories Condition=" '$(EnableLLVM)' == 'true' ">$(ExcludeCategories):InetAccess:NetworkInterfaces</ExcludeCategories>
   </PropertyGroup>
 
+  <PropertyGroup>
+    <UseMonoRuntime Condition=" '$(_AndroidTypeMapImplementation)' == 'trimmable' and '$(UseMonoRuntime)' == '' and '$(PublishAot)' != 'true' ">false</UseMonoRuntime>
+    <TestsFlavor Condition=" '$(TestsFlavor)' == '' and '$(_AndroidTypeMapImplementation)' == 'trimmable' ">CoreCLRTrimmable</TestsFlavor>
+    <ExcludeCategories Condition=" '$(_AndroidTypeMapImplementation)' == 'trimmable' ">$(ExcludeCategories):NativeTypeMap:TrimmableIgnore:SSL</ExcludeCategories>
+  </PropertyGroup>
+
   <ItemGroup>
     <PackageReference Include="Mono.Linq.Expressions" Version="2.0.0" />
   </ItemGroup>
diff --git a/tests/Mono.Android-Tests/Mono.Android-Tests/Xamarin.Android.RuntimeTests/NUnitInstrumentation.cs b/tests/Mono.Android-Tests/Mono.Android-Tests/Xamarin.Android.RuntimeTests/NUnitInstrumentation.cs
index 215fde081a9..867dab2ffb9 100644
--- a/tests/Mono.Android-Tests/Mono.Android-Tests/Xamarin.Android.RuntimeTests/NUnitInstrumentation.cs
+++ b/tests/Mono.Android-Tests/Mono.Android-Tests/Xamarin.Android.RuntimeTests/NUnitInstrumentation.cs
@@ -25,6 +25,20 @@ protected override string LogTag
         protected NUnitInstrumentation(IntPtr handle, JniHandleOwnership transfer)
             : base(handle, transfer)
         {
+            if (Microsoft.Android.Runtime.RuntimeFeature.TrimmableTypeMap) {
+                // Java.Interop-Tests fixtures that use JavaObject types (not Java.Lang.Object)
+                // don't have JCW Java classes in the trimmable APK, and method remapping
+                // tests require Java-side support not present in the trimmable path.
+                // Exclude these entire fixtures to prevent ClassNotFoundException crashes.
+                ExcludedTestNames = new [] {
+                    "Java.InteropTests.JavaObjectTest",
+                    "Java.InteropTests.InvokeVirtualFromConstructorTests",
+                    "Java.InteropTests.JniPeerMembersTests",
+                    "Java.InteropTests.JniTypeManagerTests",
+                    "Java.InteropTests.JniValueMarshaler_object_ContractTests",
+                    "Java.InteropTests.JavaExceptionTests.InnerExceptionIsNotAProxy",
+                };
+            }
         }
 
         protected override IList<TestAssemblyInfo> GetTestAssemblies()