diff --git a/system/lib/libc/musl/src/thread/__timedwait.c b/system/lib/libc/musl/src/thread/__timedwait.c
index eb1e498b879ca..4dd08f8c58c59 100644
--- a/system/lib/libc/musl/src/thread/__timedwait.c
+++ b/system/lib/libc/musl/src/thread/__timedwait.c
@@ -59,20 +59,16 @@ int __timedwait_cp(volatile int *addr, int val,
 
 #ifdef __EMSCRIPTEN__
 	double msecsToSleep = top ? (top->tv_sec * 1000 + top->tv_nsec / 1000000.0) : INFINITY;
-	int is_runtime_thread = emscripten_is_main_runtime_thread();
-
-	// Main runtime thread may need to run proxied calls, so sleep in very small slices to be responsive.
-	double max_ms_slice_to_sleep = is_runtime_thread ? 1 : 100;
 
 	// cp suffix in the function name means "cancellation point", so this wait can be cancelled
 	// by the users unless current threads cancelability is set to PTHREAD_CANCEL_DISABLE
 	// which may be either done by the user of __timedwait() function.
-	if (is_runtime_thread ||
-	    pthread_self()->canceldisable != PTHREAD_CANCEL_DISABLE ||
-	    pthread_self()->cancelasync) {
+	pthread_t self = pthread_self();
+	if (!self->canceldisable) {
+		double max_ms_slice_to_sleep = 100;
 		double sleepUntilTime = emscripten_get_now() + msecsToSleep;
 		do {
-			if (pthread_self()->cancel) {
+			if (self->cancel) {
 				// The thread was canceled by pthread_cancel().
 				// In the case of cancelasync or PTHREAD_CANCEL_ENABLE we can just call
 				// __pthread_testcancel(), which won't return at all.
diff --git a/system/lib/pthread/emscripten_futex_wait.c b/system/lib/pthread/emscripten_futex_wait.c
index c7265abe84c73..88e6533a5ff5f 100644
--- a/system/lib/pthread/emscripten_futex_wait.c
+++ b/system/lib/pthread/emscripten_futex_wait.c
@@ -48,7 +48,8 @@ static int futex_wait_main_browser_thread(volatile void* addr,
 
   while (1) {
 #ifdef __EMSCRIPTEN_PTHREADS__
-    if (cancelable && pthread_self()->cancel) {
+    if (cancelable) {
+      __pthread_testcancel();
       return -ETIMEDOUT;
     }
 #endif
@@ -130,7 +131,8 @@ int emscripten_futex_wait(volatile void *addr, uint32_t val, double max_wait_ms)
   emscripten_conditional_set_current_thread_status(EM_THREAD_STATUS_RUNNING, EM_THREAD_STATUS_WAITFUTEX);
 
 #ifdef __EMSCRIPTEN_PTHREADS__
-  bool cancelable = pthread_self()->cancelasync == PTHREAD_CANCEL_ASYNCHRONOUS;
+  pthread_t self = pthread_self();
+  bool cancelable = self->cancelasync;
 #else
   bool cancelable = false;
 #endif
@@ -211,8 +213,8 @@ int emscripten_futex_wait(volatile void *addr, uint32_t val, double max_wait_ms)
     }
 #endif
 #ifdef __EMSCRIPTEN_PTHREADS__
-    if (cancelable && ret == ATOMICS_WAIT_TIMED_OUT && pthread_self()->cancel) {
-      // Break out of the loop early if we were cancelled
+    if (cancelable && ret == ATOMICS_WAIT_TIMED_OUT) {
+      __pthread_testcancel();
       break;
     }
     // If remainder_ns is negative it means we want wait forever, and we don't
diff --git a/test/codesize/test_codesize_minimal_pthreads.json b/test/codesize/test_codesize_minimal_pthreads.json
index da85c8790e0ef..e57a28af67193 100644
--- a/test/codesize/test_codesize_minimal_pthreads.json
+++ b/test/codesize/test_codesize_minimal_pthreads.json
@@ -1,10 +1,10 @@
 {
   "a.out.js": 7364,
   "a.out.js.gz": 3607,
-  "a.out.nodebug.wasm": 19265,
-  "a.out.nodebug.wasm.gz": 8934,
-  "total": 26629,
-  "total_gz": 12541,
+  "a.out.nodebug.wasm": 19231,
+  "a.out.nodebug.wasm.gz": 8905,
+  "total": 26595,
+  "total_gz": 12512,
   "sent": [
     "a (memory)",
     "b (emscripten_get_now)",
diff --git a/test/codesize/test_codesize_minimal_pthreads_memgrowth.json b/test/codesize/test_codesize_minimal_pthreads_memgrowth.json
index a96e1eea00ba9..6a535bf1fe27d 100644
--- a/test/codesize/test_codesize_minimal_pthreads_memgrowth.json
+++ b/test/codesize/test_codesize_minimal_pthreads_memgrowth.json
@@ -1,10 +1,10 @@
 {
   "a.out.js": 7766,
   "a.out.js.gz": 3812,
-  "a.out.nodebug.wasm": 19266,
-  "a.out.nodebug.wasm.gz": 8935,
-  "total": 27032,
-  "total_gz": 12747,
+  "a.out.nodebug.wasm": 19234,
+  "a.out.nodebug.wasm.gz": 8919,
+  "total": 27000,
+  "total_gz": 12731,
   "sent": [
     "a (memory)",
     "b (emscripten_get_now)",
diff --git a/test/pthread/test_pthread_cancel_async.c b/test/pthread/test_pthread_cancel_async.c
index 8b0a43416cd83..f9739e3a48cda 100644
--- a/test/pthread/test_pthread_cancel_async.c
+++ b/test/pthread/test_pthread_cancel_async.c
@@ -11,14 +11,24 @@
 #include <assert.h>
 #include <unistd.h>
 #include <errno.h>
+
+#ifdef __EMSCRIPTEN__
 #include <emscripten/console.h>
+#else
+void emscripten_out(const char* msg) {
+  printf("%s\n", msg);
+}
+
+void emscripten_outf(const char* msg, ...) {
+  printf("%s\n", msg);
+}
+#endif
 
 pthread_mutex_t mutex = PTHREAD_MUTEX_INITIALIZER;
 _Atomic long res = 43;
 _Atomic int started = false;
 
-static void cleanup_handler(void *arg)
-{
+static void cleanup_handler(void *arg) {
   long a = (long)arg;
   emscripten_outf("Called clean-up handler with arg %ld", a);
   res -= a;