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As @murphycj2 has done in the biometrics package, lets make this package use pysamstats (which really just calls to pysam) in the same way:
- Ensure
stepperis not eliminating duplicate reads (usenofilter?) Include duplicate reads for pileup alimanfoo/pysamstats#91 - Figure out a way to avoid double-counting overlapping reads (
ignore_overlapparam does not get passed to pysam... Counting overlapping read-pairs alimanfoo/pysamstats#98) - Set
min_mapping_qualitytruncateandmax_depthdefaults to same value as biometrics (and ensure they are exposed as parameters) - Can we be consistent with
min_base_qualityor do the noise and fingerprinting require different values for this to work? - We might still want to consider the possibility of combining these two calculations into the same package
murphycj2
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