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Achievement: Pull SharkAchievement: Pair Extraordinaire

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JuntongLai/README.md

Juntong Lai, PhD

Postdoctoral Research Associate (PDRA) · INSIGNEO Institute for in silico Medicine · University of Sheffield

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About

I am an early-career researcher working at the interface of mathematical modelling, computational biomechanics, and multi-scale modelling. My doctoral research, conducted within the INSIGNEO Institute for in silico Medicine at the University of Sheffield, develops mechanistic models of musculoskeletal disease and systemic disease with a particular focus on osteoarthritis, obesity-driven inflammation, and spine biomechanics.

Selected Publications

Full list on ORCID · personal website

[1] Lai J, Lacroix D (2026). A computational study of adiposity-associated factors in the inflammatory process of osteoarthritis. Journal of Theoretical Biology, 625: 112429. https://doi.org/10.1016/j.jtbi.2026.112429

[2] Lai J, Lacroix D (2025). Mathematical modelling of inflammatory process and obesity in osteoarthritis. PLOS ONE, 20(6): e0323258. https://doi.org/10.1371/journal.pone.0323258

[3] Lai J, Tomlinson J, Breakwell L, Lacroix D (2025). A finite element study of the effect of cross-link stabilisation in a lumbar spine tumour model. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. https://doi.org/10.1177/09544119251348279

Affiliation

University of Sheffield — School of Mechanical, Aerospace and Civil Engineering INSIGNEO Institute for in silico Medicine — a multidisciplinary research institute of 260+ academics and clinicians pioneering computational approaches to healthcare

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  1. MCD-OA MCD-OA Public

    We propose a mechanobiological cartilage degeneration framework in osteoarthritis (MCD-OA), which couples mechanical loading and biological processes, in the context of obesity.

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