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41 changes: 41 additions & 0 deletions datasets/hprc-epigenome.yaml
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Name: Epigenomes of the Human Pangenome Reference Consortium (HPRC) Release 2
Description: |
The Human Pangenome Reference Consortium (HPRC) Release 2 represents a landmark achievement in genomics, providing high-quality phased genome assemblies from over 200 individuals with comprehensive functional genomics data. The HPRC Epigenome Browser provides researchers a way to explore all epigenomics data generated by release 2. The HPRC Epigenome Browser (HPRCEB) is a modern, interactive web portal that democratizes access to HPRC Release 2 epigenomics data through an intuitive interface supporting genome selection, data visualization, and bulk download capabilities. The portal integrates genome assemblies, DNA methylation profiles, gene expression data, and chromatin accessibility measurements across diverse populations, enabling researchers to efficiently identify and retrieve datasets matching their specific research needs.
Contact: [email protected]
ManagedBy: Ting Wang Lab (https://wang.wustl.edu/)
Documentation: https://epigenome.humanpangenome.org/?tab=tutorials
UpdateFrequency: Annual. The repository will be updated with each new batch of data as it is generated and released under the next HPRC yearly cycle.
Tags:
- biology
- bioinformatics
- genetic
- genomic
- life sciences
- PacBio
- ONT
- Fiber-seq
License: External data users may freely download, analyze, and publish results based on any HPRC data provided here without restrictions.
Resources:
- Description: HPRC Epigenome Browser
ARN: arn:aws:s3:::hprc-epigenome
Region: us-west-2
Type: S3 Bucket
DataAtWork:
Tutorials:
- Title: |
Get To Know A Dataset: HPRC Epigenome
URL: https://github.com/twlab/open-data-examples/blob/main/get-to-know-hprc-epigenome.ipynb
AuthorName: HPRC Epigenome Browser
AuthorURL: https://epigenome.humanpangenome.org/
Publications:
- Title: A draft human pangenome reference
URL: https://doi.org/10.1038/s41586-023-05896-x
AuthorName: Liao, WW., Asri, M., Ebler, J. et al.
- Title: |
Modbed track: Visualization of modified bases in single-molecule sequencing
URL: https://www.sciencedirect.com/science/article/pii/S2666979X23002999?via%3Dihub
AuthorName: Daofeng Li, Xiaoyu Zhuo, Jessica K. Harrison, Shane Liu, Ting Wang
- Title: WashU Epigenome Browser update 2025
URL: https://doi.org/10.1093/nar/gkaf387
AuthorName: Chanrung Seng, Shane Liu, Wenjin Zhang, Xiaoyu Zhuo, Daofeng Li, Ting Wang